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Although after spinal cord injury (SCI), endogenous neural stem cells (NSCs) are activated near the damaged site, few NSCs migrate to the injury epicenter and differentiate into neurons. According to the studies, the implantation of hydrogel scaffolds loaded with...

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The researchers of OmidAfrinan company developed a 3D scaffold containing beta tricalcium phosphate particles for the treatment of skull bone defects using 3D bioprinting method. After passing the in vitro tests, this scaffold was further evaluated for the repair...

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Fabrication of scaffolds and then cell seeding is one of the common methods in tissue engineering. Although synthetic polymers have adequate mechanical properties to replace some bone tissues, they are generally hydrophobic and do not have any specific cell...

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Intraoperative bioprinting (IOB) refers to the bioprinting process performed on a live subject in a surgical setting. The technique is intended to allow surgeons to rapidly fill bony defects that would not easily heal by themselves and they used...

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In a groundbreaking new study, researchers at the University of Minnesota have 3D printed a functioning centimeter-scale human heart pump in the lab. Videos show the production of the human heart using a 3D bioprinter and its function in...

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A team of researchers at Texas A&M University (TX, USA) have developed and grown a bioprinted blood vessel able to mimic specific states of health and disease, allowing for the possibility of precision cardiovascular drug advancements. reference: Gold KA,...

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  Recently researchers at the National University of Singapore, have been used chitosan methacrylate and PCL as base hydrogel and backing layer respectively to fabricate customizable wound dressings via 3D printing. Synthesized chitosan methacrylate is evaluated to be printable,...

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Researchers have used the digital light processing (DLP) printing technique to develop dexamethasone-loaded punctal plugs. In this study, dexamethasone was used as an anti-inflammatory steroid drug in the treatment of corneal diseases. Punctal plugs with different drug loadings were...

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An integrated and heterogeneous soft-hard construct was successfully assembled as a lock-key structure by 3D cell printing. This 3D printed soft-hard construct has the potential to be a customized plug in alveolar ridge preservation. reference: Zhang, S., Li, Q.,...

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Recently, Korean researchers presents a method for producing hepatic-lobule-like microtissue spheroids using a bioprinting system and microfluidic emulsification system.  A noteworthy point in this study is the use of a precursor cartridge to create a specific pattern in how...

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A group of researchers has developed a printed structure composed of GelMA and Alginate bioinks with anisotropic mechanical properties. In this study, it was shown that the mechanical properties of the scaffold can be tunable by creating a striped...

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Researchers at the University of California have developed a high-throughput technique for 3D bioprinting. Their printing method can yield a 96-well plate with tissue samples in each well in as little as 30 minutes. This approach would be useful...

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In a study by Cellink researchers, a full thickness skin tissue model was bioprinted. In this study, the dermis was bioprinted using primary dermal fibroblasts embedded in GelMA based bioink, and the epidermis, containing a high concentration of keratinocytes...

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AllGbone©, the new product of Omidafarinan Co. is a bioink based on extracellular matrix (ECM) of natural bone tissue, which is designed and developed for bone tissue engineering applications. The superiority of this product over the others is its...

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Four-dimensional (4D) bioprinting, in which the concept of time is integrated with three-dimensional (3D) bioprinting as the fourth dimension, with the goal of constructing complex, functional structures. 4D bioprinting can be used to fabricate dynamic 3D-patterned biological architectures that...

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Multicomponent self-assembling bioinks offer a unique opportunity to recreate chemical and mechanical features of the ECM and selective communication with cells. Liquid-in-liquid printing, the inoculation of one low viscosity liquid phase into another, offers an opportunity to design bioink...

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Fixing traumatic injuries to the skin and bones of the face and skull is difficult because of the many layers of different types of tissues involved, but now, researchers have repaired such defects in a rat model using bioprinting...

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Researchers developed a four axis extrusion-based additive manufacturing system based on fused deposition modeling (FDM) to create tubular hollow scaffolds. With this technique systematic changes in design can be made to alter the mechanical properties for the targeted tissue...

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Serpooshan Awarded NSF CAREER Award to Bioprint a 3D Model of the Developing Human Heart. The project focuses on understanding normal heart development and what can go wrong in those processes and lead to severe defects. reference: https://bme.gatech.edu/bme/serpooshan-awarded-nsf-career-award-bioprint-3d-model-developing-human-heart

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Combined delivery of stem cells with the controlled release of osteogenic factors, within a mechanically-strong biomaterial combined during manufacturing would replace injectable defect fillers (cements) and allow personalized implants to be rapidly prototyped by 3D bioprinting. To this end,...

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With the aim of understanding cellular interactions of hepatocytes in their physiological microenvironment and to generate an artificial 3D in vitro model of liver, a co-culture system using 3D extrusion bioprinting was developed. In this method, bio-ink based on...

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Researchers have developed the first 3D-printable ‘bottlebrush’ elastomer. The new material results in printed objects that have unusual softness, elasticity and mechanical properties that closely resemble those of human tissue. Unique molecular structure of bottlebrush elastomers facilitate bioprinting in...

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A collaboration led by researchers at Carnegie Mellon University (PA, USA) has reported a COVID-19 antibody detection method created using aerosol jet 3D printing able to report detection within seconds, a breakthrough that could significantly improve studies of vaccine...

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A team of researchers at UNSW (Sydney, Australia) develops a novel, ceramic-based ink to print bone-like structures that harden within minutes of being placed in water.   REFERENCE: Romanazzo S, Molley TG, Nemec S et al. Synthetic bone-like structures...