Recently, Korean researchers presents a method for producing hepatic-lobule-like microtissue spheroids using a bioprinting system and microfluidic emulsification system.  A noteworthy point in this study is the use of a precursor cartridge to create a specific pattern in how cells are located in the spheroid.

reference:

Hong, G., Kim, J., Oh, H., Yun, S., Kim, C.M., Jeong, Y.M., Yun, W.S., Shim, J.H., Jang, I., Kim, C.Y. and Jin, S., Production of Multiple Cell‐Laden Microtissue Spheroids with a Biomimetic Hepatic‐Lobule‐Like Structure. Advanced Materials, p.2102624.