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تصویر: ۳D Printed Punctal Plugs for Controlled Ocular Drug Delivery

۳D Printed Punctal Plugs for Controlled Ocular Drug Delivery

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Researchers have used the digital light processing (DLP) printing technique to develop dexamethasone-loaded punctal plugs. In this study, dexamethasone was used as an anti-inflammatory steroid drug in the treatment of corneal diseases. Punctal plugs with different drug loadings were...

تصویر: Three-Dimensional Cell Printed Lock-Key Structure for Oral Soft and Hard Tissue Regeneration

Three-Dimensional Cell Printed Lock-Key Structure for Oral Soft and Hard Tissue Regeneration

An integrated and heterogeneous soft-hard construct was successfully assembled as a lock-key structure by 3D cell printing. This 3D printed soft-hard construct has the potential to be a customized plug in alveolar ridge preservation. reference: Zhang, S., Li, Q.,...

تصویر: ۳D bio printed spheroid with lobule-like constructs and liver functions

۳D bio printed spheroid with lobule-like constructs and liver functions

Recently, Korean researchers presents a method for producing hepatic-lobule-like microtissue spheroids using a bioprinting system and microfluidic emulsification system.  A noteworthy point in this study is the use of a precursor cartridge to create a specific pattern in how...

تصویر: Development of 3D bioprinted GelMA-alginate hydrogels with tunable mechanical properties

Development of 3D bioprinted GelMA-alginate hydrogels with tunable mechanical properties

A group of researchers has developed a printed structure composed of GelMA and Alginate bioinks with anisotropic mechanical properties. In this study, it was shown that the mechanical properties of the scaffold can be tunable by creating a striped...

تصویر: High throughput direct 3D bioprinting (HT-3DP) in multiwell plates

High throughput direct 3D bioprinting (HT-3DP) in multiwell plates

Researchers at the University of California have developed a high-throughput technique for 3D bioprinting. Their printing method can yield a 96-well plate with tissue samples in each well in as little as 30 minutes. This approach would be useful...

تصویر: ۳d bioprining skin tissues model using primary cells

۳d bioprining skin tissues model using primary cells

In a study by Cellink researchers, a full thickness skin tissue model was bioprinted. In this study, the dermis was bioprinted using primary dermal fibroblasts embedded in GelMA based bioink, and the epidermis, containing a high concentration of keratinocytes...

تصویر: Restoration of bone lesions using a bioink based on bone allograft, the latest bioink product of OmidAfarinan Co.

Restoration of bone lesions using a bioink based on bone allograft, the latest bioink product of OmidAfarinan Co.

AllGbone©, the new product of Omidafarinan Co. is a bioink based on extracellular matrix (ECM) of natural bone tissue, which is designed and developed for bone tissue engineering applications. The superiority of this product over the others is its...

تصویر: Four-dimensional bioprinting

Four-dimensional bioprinting

Four-dimensional (4D) bioprinting, in which the concept of time is integrated with three-dimensional (3D) bioprinting as the fourth dimension, with the goal of constructing complex, functional structures. 4D bioprinting can be used to fabricate dynamic 3D-patterned biological architectures that...

تصویر: A self-assembling bioink for fabricating vascular-like structures

A self-assembling bioink for fabricating vascular-like structures

Multicomponent self-assembling bioinks offer a unique opportunity to recreate chemical and mechanical features of the ECM and selective communication with cells. Liquid-in-liquid printing, the inoculation of one low viscosity liquid phase into another, offers an opportunity to design bioink...

تصویر: Bioprinting both bone and soft tissues during surgery simultaneously

Bioprinting both bone and soft tissues during surgery simultaneously

Fixing traumatic injuries to the skin and bones of the face and skull is difficult because of the many layers of different types of tissues involved, but now, researchers have repaired such defects in a rat model using bioprinting...

تصویر: Four-axis 3D printing for the fabrication of tubular scaffolds with tailorable mechanical properties

Four-axis 3D printing for the fabrication of tubular scaffolds with tailorable mechanical properties

Researchers developed a four axis extrusion-based additive manufacturing system based on fused deposition modeling (FDM) to create tubular hollow scaffolds. With this technique systematic changes in design can be made to alter the mechanical properties for the targeted tissue...

تصویر: Serpooshan Awarded NSF CAREER Award to Bioprint a 3D Model of the Developing Human Heart

Serpooshan Awarded NSF CAREER Award to Bioprint a 3D Model of the Developing Human Heart

Serpooshan Awarded NSF CAREER Award to Bioprint a 3D Model of the Developing Human Heart. The project focuses on understanding normal heart development and what can go wrong in those processes and lead to severe defects. reference: https://bme.gatech.edu/bme/serpooshan-awarded-nsf-career-award-bioprint-3d-model-developing-human-heart

تصویر: Genetically-programmed, cell-laden & mechanically strong 3D bioprinted scaffolds for bone repair

Genetically-programmed, cell-laden & mechanically strong 3D bioprinted scaffolds for bone repair

Combined delivery of stem cells with the controlled release of osteogenic factors, within a mechanically-strong biomaterial combined during manufacturing would replace injectable defect fillers (cements) and allow personalized implants to be rapidly prototyped by 3D bioprinting. To this end,...

تصویر: An in-vitro liver model using 3D bioprinting core–shell structure of hepatocytes and fibroblasts

An in-vitro liver model using 3D bioprinting core–shell structure of hepatocytes and fibroblasts

With the aim of understanding cellular interactions of hepatocytes in their physiological microenvironment and to generate an artificial 3D in vitro model of liver, a co-culture system using 3D extrusion bioprinting was developed. In this method, bio-ink based on...

تصویر: The first 3D-printable ‘bottlebrush’ elastomer

The first 3D-printable ‘bottlebrush’ elastomer

Researchers have developed the first 3D-printable ‘bottlebrush’ elastomer. The new material results in printed objects that have unusual softness, elasticity and mechanical properties that closely resemble those of human tissue. Unique molecular structure of bottlebrush elastomers facilitate bioprinting in...

تصویر: Manufacturing of the 3D printed COVID-19 rapid test chip (3DcC) by Aerosol Jet nanoparticle 3D printing

Manufacturing of the 3D printed COVID-19 rapid test chip (3DcC) by Aerosol Jet nanoparticle 3D printing

A collaboration led by researchers at Carnegie Mellon University (PA, USA) has reported a COVID-19 antibody detection method created using aerosol jet 3D printing able to report detection within seconds, a breakthrough that could significantly improve studies of vaccine...

تصویر: Ceramic-based ink to 3D-print bone parts with living cells

Ceramic-based ink to 3D-print bone parts with living cells

A team of researchers at UNSW (Sydney, Australia) develops a novel, ceramic-based ink to print bone-like structures that harden within minutes of being placed in water.   REFERENCE: Romanazzo S, Molley TG, Nemec S et al. Synthetic bone-like structures...

تصویر: ۳D Bioprinted Alginate patches for cardiovascular disease

۳D Bioprinted Alginate patches for cardiovascular disease

A team of Iranian researchers used a novel technique to print sodium alginate cardiac patches using OmidAfarinan bioprinters. The results indicated that the prepared patch can be a suitable candidate for treating the cardiac scars after cardiovascular disease. reference:...

تصویر: Bioprinted, personalized scaffolds for ankle joint tissue regeneration in development.

Bioprinted, personalized scaffolds for ankle joint tissue regeneration in development.

The TRIANKLE consortium made up of 12 European organizations has come together to develop bioprinted, personalized scaffolds for ankle joint tissue regeneration.   reference: https://www.3dmednet.com/ https://www.cellink.com/

تصویر: Nucleotide lipid-based hydrogel as a new route to produce crosslinker-free scaffolds

Nucleotide lipid-based hydrogel as a new route to produce crosslinker-free scaffolds

Despite recent advances in tissue engineering and biofabrication, progress has been limited to the development of bioinks based on polymers.  Scientist show that a nucleotide lipid-based hydrogel resulting from the self-assembly of nucleotide lipids can be used as a...

تصویر: ۳D bioprinting of anisotropic engineered tissue constructs with ultrasonically induced cell patterning

۳D bioprinting of anisotropic engineered tissue constructs with ultrasonically induced cell patterning

US researchers have developed a new bioprinting technique that uses ultrasonic standing bulk acoustic waves (SBAW) to organize cells into controllable anisotropic patterns within viscous bioinks while maintaining high cell viability. This work represents a step forward in advancing...

تصویر: Fabrication of Three-Dimensional Composite Scaffold for Simultaneous Alveolar Bone Regeneration in Dental Implant Installation

Fabrication of Three-Dimensional Composite Scaffold for Simultaneous Alveolar Bone Regeneration in Dental Implant Installation

Korean researchers have designed a 3D printed composite scaffold that can be combined simultaneously with bone grafts and fixtures to minimize the cost and duration of dental implant surgery. Further, by using 3D printing technology in making this implant,...

تصویر: Mini-kidneys bioprinted for toxicology research and treatment developments

Mini-kidneys bioprinted for toxicology research and treatment developments

A team of Australian researchers apply extrusion-based three-dimensional cellular bioprinting to deliver rapid and high-throughput generation of kidney organoids with highly reproducible cell number and viability. Automated extrusion-based bioprinting for kidney organoid production delivers improvements in throughput, quality control,...

تصویر: Evaluation of the effects of cell-dispensing using an inkjet-based bioprinter on cell integrity

Evaluation of the effects of cell-dispensing using an inkjet-based bioprinter on cell integrity

Japanese researchers have developed a stress-free and media-direct-dispensing inkjet bioprinter that exhibited cell-friendly dispensing performance, which was similar to the manual dispensing operation, based not only on cell viability but also on gene expression levels. reference: https://www.nature.com/articles/s41598-020-64193-z Yumoto M,...