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تصویر: ۳D Bioprinted Multicellular Vascular Models

۳D Bioprinted Multicellular Vascular Models

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A team of researchers at Texas A&M University (TX, USA) have developed and grown a bioprinted blood vessel able to mimic specific states of health and disease, allowing for the possibility of precision cardiovascular drug advancements. reference: Gold KA,...

تصویر: ۳D Printed Punctal Plugs for Controlled Ocular Drug Delivery

۳D Printed Punctal Plugs for Controlled Ocular Drug Delivery

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Researchers have used the digital light processing (DLP) printing technique to develop dexamethasone-loaded punctal plugs. In this study, dexamethasone was used as an anti-inflammatory steroid drug in the treatment of corneal diseases. Punctal plugs with different drug loadings were...

تصویر: ۳D bio printed spheroid with lobule-like constructs and liver functions

۳D bio printed spheroid with lobule-like constructs and liver functions

Recently, Korean researchers presents a method for producing hepatic-lobule-like microtissue spheroids using a bioprinting system and microfluidic emulsification system.  A noteworthy point in this study is the use of a precursor cartridge to create a specific pattern in how...

تصویر: Four-axis 3D printing for the fabrication of tubular scaffolds with tailorable mechanical properties

Four-axis 3D printing for the fabrication of tubular scaffolds with tailorable mechanical properties

Researchers developed a four axis extrusion-based additive manufacturing system based on fused deposition modeling (FDM) to create tubular hollow scaffolds. With this technique systematic changes in design can be made to alter the mechanical properties for the targeted tissue...

تصویر: Serpooshan Awarded NSF CAREER Award to Bioprint a 3D Model of the Developing Human Heart

Serpooshan Awarded NSF CAREER Award to Bioprint a 3D Model of the Developing Human Heart

Serpooshan Awarded NSF CAREER Award to Bioprint a 3D Model of the Developing Human Heart. The project focuses on understanding normal heart development and what can go wrong in those processes and lead to severe defects. reference: https://bme.gatech.edu/bme/serpooshan-awarded-nsf-career-award-bioprint-3d-model-developing-human-heart

تصویر: An in-vitro liver model using 3D bioprinting core–shell structure of hepatocytes and fibroblasts

An in-vitro liver model using 3D bioprinting core–shell structure of hepatocytes and fibroblasts

With the aim of understanding cellular interactions of hepatocytes in their physiological microenvironment and to generate an artificial 3D in vitro model of liver, a co-culture system using 3D extrusion bioprinting was developed. In this method, bio-ink based on...

تصویر: The first 3D-printable ‘bottlebrush’ elastomer

The first 3D-printable ‘bottlebrush’ elastomer

Researchers have developed the first 3D-printable ‘bottlebrush’ elastomer. The new material results in printed objects that have unusual softness, elasticity and mechanical properties that closely resemble those of human tissue. Unique molecular structure of bottlebrush elastomers facilitate bioprinting in...

تصویر: ۳D bioprinting of anisotropic engineered tissue constructs with ultrasonically induced cell patterning

۳D bioprinting of anisotropic engineered tissue constructs with ultrasonically induced cell patterning

US researchers have developed a new bioprinting technique that uses ultrasonic standing bulk acoustic waves (SBAW) to organize cells into controllable anisotropic patterns within viscous bioinks while maintaining high cell viability. This work represents a step forward in advancing...

تصویر: Mini-kidneys bioprinted for toxicology research and treatment developments

Mini-kidneys bioprinted for toxicology research and treatment developments

A team of Australian researchers apply extrusion-based three-dimensional cellular bioprinting to deliver rapid and high-throughput generation of kidney organoids with highly reproducible cell number and viability. Automated extrusion-based bioprinting for kidney organoid production delivers improvements in throughput, quality control,...

تصویر: Evaluation of the effects of cell-dispensing using an inkjet-based bioprinter on cell integrity

Evaluation of the effects of cell-dispensing using an inkjet-based bioprinter on cell integrity

Japanese researchers have developed a stress-free and media-direct-dispensing inkjet bioprinter that exhibited cell-friendly dispensing performance, which was similar to the manual dispensing operation, based not only on cell viability but also on gene expression levels. reference: https://www.nature.com/articles/s41598-020-64193-z Yumoto M,...

تصویر: Vascularized cell-laden 3D bioprinted wound dressings for regenerative medicine applications

Vascularized cell-laden 3D bioprinted wound dressings for regenerative medicine applications

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Using three-dimensional printed structures with vascular networks is considered as a novel cell-based therapy for regenerative medicine applications. A team of researchers at the University of Otago (New Zealand) reports a promising strategy using core shell extrusion 3D bioprinting...

تصویر: ۳D Printing of Bone Grafts for Cleft Alveolar Osteoplasty

۳D Printing of Bone Grafts for Cleft Alveolar Osteoplasty

One of the most common hereditary craniofacial anomalies in humans are cleft lip and cleft alveolar bone with or without cleft palate. German researchers developed a novel therapy concept based on 3D printing of biodegradable calcium phosphate-based materials allowing...

تصویر: Enhancement of 3D cell printing by using silk nanofibers

Enhancement of 3D cell printing by using silk nanofibers

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In a study recently published in Materials Today Bio, researchers from Osaka University have used silk nanofibers obtained by mechanical disintegration to enhance the printing process without damaging the cells or cell assemblies. reference: https://www.3dmednet.com/silk-fibers-provide-integrity-and-prevent-cell-damage-in-3d-printed-biological-constructs/ Sakai S, Yoshii A,...

تصویر: ۳D-printed capsule could collect bacteria from throughout the gastrointestinal tract

۳D-printed capsule could collect bacteria from throughout the gastrointestinal tract

A novel 3D-printed capsule, developed by a team at Purdue University (IL, USA), could allow for the collection of bacteria samples from throughout the gastrointestinal tract, improving on conventional sampling methods that may exclude areas for bacteria collection outside...

تصویر: Emerging Trends of Bioengineering Technologies: Webinars by International Speakers

Emerging Trends of Bioengineering Technologies: Webinars by International Speakers

The new round of 3D Bio Club webinars titled “Emerging Trends of Bioengineering Technologies” is organized in collaboration of OmidAfarinan and RASA companies. In this section of webinars, international speakers talk about new trends in bioengineering, especially 3D bioprinting,...

تصویر: The First 3D Bioprinting Experiment In Space Is Achieved

The First 3D Bioprinting Experiment In Space Is Achieved

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In a collaboration between the Geneva Foundation (Geneva), the Uniformed Services University of the Health Sciences (USU), commercial space company TechShot, Inc, and 3D printer manufacturer nScrypt, Inc, the first bioprinting project in space about the engineering of the...

تصویر: ۳D bioprinting of constructs made of hydrogels and thermoplastic polymers for articular cartilage engineering

۳D bioprinting of constructs made of hydrogels and thermoplastic polymers for articular cartilage engineering

In a national collaboration of Spain scientists, a new bio-ink made of alginate and hyaluronic acid was developed for articular cartilage engineering. To provide the mechanical properties required in cartilage tissue, Polylactic acid was co-printed with the cell-encapsulated hydrogel....

تصویر: ۳D-Printing Responds to Covid-19 Outbreak: A Review on Simple and Feasible Ideas

۳D-Printing Responds to Covid-19 Outbreak: A Review on Simple and Feasible Ideas

With the outbreak of the coronavirus, the daily activities have been significantly disrupted. Therefore, the efforts of many research institutes in the world are focused on combating the spread of the virus. In this session of 3D Bio Club,...

تصویر: Priming mesenchymal stem cells in vivo: A game-changer to treat myocardial infarction induced hearts

Priming mesenchymal stem cells in vivo: A game-changer to treat myocardial infarction induced hearts

Despite the great potential of mesenchymal stem cells in various regeneration therapies, their application to treat myocardial infarction (MI)–induced hearts is limited. In  recent research by an international joint research team of POSTECH, Seoul St. Mary’s Hospital, and City...

تصویر: Development of functional scaffolds for bone tissue engineering using 3D-bioprinting

Development of functional scaffolds for bone tissue engineering using 3D-bioprinting

Extrusion-based 3D-printing is among the additive manufacturing (AM) techniques that have attracted much attention for the fabrication of bone tissue engineering scaffolds with defined geometries and internal structure. The aim of the studies performed in this thesis was to...

تصویر: Development of high performance nano- bioink

Development of high performance nano- bioink

Despite considerable development of bioprinting methods, real applications in tissue engineering are still limited due to challenges in development of a suitable bioink with high printability and cell viability. Therefore, we will host Dr. Zandi for the introduction of...

تصویر: ۳D-Bio Club: 3D Bioprinting novel applications

۳D-Bio Club: 3D Bioprinting novel applications

Due to Covid-19 outbreak, OmidAfarinan team decided to hold an online webinar entitled “۳D Bioprinting Novel Applications” from “۳D-Bio Club” series. In this session, Mr. Majid Hajihosseinali as the co-founder and CEO at OmidAfarinan Company, will discuss the recent...

تصویر: (A Handheld 3D Bioprinter is Developed to Reconstruct Volumetric Muscle Loss (VML

(A Handheld 3D Bioprinter is Developed to Reconstruct Volumetric Muscle Loss (VML

Reconstructive surgery is yet not successful in the regeneration of volumetric muscle loss (VML). The defect geometry is patient dependent which limits the reliability of many common methods. 3D bioprinting, as a new emerging technology, can circumvent many of...

تصویر: The importance of neural and muscular cells integration in 3D bioprinted skeletal muscle constructs

The importance of neural and muscular cells integration in 3D bioprinted skeletal muscle constructs

Regenerative medicine has been promised regeneration of muscular constructs that mimic structural and functional characteristics of native skeletal muscles. Recently, scientists at Wake Forest Institute for Regenerative Medicine (WFIRM), have accelerated restoration of skeletal muscle through integration of neural...