Coaxial 3D printing of hierarchical structured hydrogel scaffolds for repair of spinal cord injury
In vivo evaluation of bone scaffold fabricated by 3D bioprinting method by researchers of OmidAfrinan company
Fabrication of 3D printed hybrid scaffolds carrying dental pulp stem cells
Bioprinting Bone Constructs During Surgery
The beating of the first bioprinted human heart created from stem cells
۳D Bioprinted Multicellular Vascular Models
۳D Printed Punctal Plugs for Controlled Ocular Drug Delivery
Coaxial 3D printing of hierarchical structured hydrogel scaffolds for repair of spinal cord injury
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Although after spinal cord injury (SCI), endogenous neural stem cells (NSCs) are activated near the damaged site, few NSCs migrate to the injury epicenter and differentiate into neurons. According to the studies, the implantation of hydrogel scaffolds loaded with...
In vivo evaluation of bone scaffold fabricated by 3D bioprinting method by researchers of OmidAfrinan company
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The researchers of OmidAfrinan company developed a 3D scaffold containing beta tricalcium phosphate particles for the treatment of skull bone defects using 3D bioprinting method. After passing the in vitro tests, this scaffold was further evaluated for the repair...
Fabrication of 3D printed hybrid scaffolds carrying dental pulp stem cells
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Fabrication of scaffolds and then cell seeding is one of the common methods in tissue engineering. Although synthetic polymers have adequate mechanical properties to replace some bone tissues, they are generally hydrophobic and do not have any specific cell...
Bioprinting Bone Constructs During Surgery
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Intraoperative bioprinting (IOB) refers to the bioprinting process performed on a live subject in a surgical setting. The technique is intended to allow surgeons to rapidly fill bony defects that would not easily heal by themselves and they used...
The beating of the first bioprinted human heart created from stem cells
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In a groundbreaking new study, researchers at the University of Minnesota have 3D printed a functioning centimeter-scale human heart pump in the lab. Videos show the production of the human heart using a 3D bioprinter and its function in...
Three-Dimensional Cell Printed Lock-Key Structure for Oral Soft and Hard Tissue Regeneration
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An integrated and heterogeneous soft-hard construct was successfully assembled as a lock-key structure by 3D cell printing. This 3D printed soft-hard construct has the potential to be a customized plug in alveolar ridge preservation. reference: Zhang, S., Li, Q.,...
Development of 3D bioprinted GelMA-alginate hydrogels with tunable mechanical properties
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A group of researchers has developed a printed structure composed of GelMA and Alginate bioinks with anisotropic mechanical properties. In this study, it was shown that the mechanical properties of the scaffold can be tunable by creating a striped...
High throughput direct 3D bioprinting (HT-3DP) in multiwell plates
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Researchers at the University of California have developed a high-throughput technique for 3D bioprinting. Their printing method can yield a 96-well plate with tissue samples in each well in as little as 30 minutes. This approach would be useful...
۳d bioprining skin tissues model using primary cells
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In a study by Cellink researchers, a full thickness skin tissue model was bioprinted. In this study, the dermis was bioprinted using primary dermal fibroblasts embedded in GelMA based bioink, and the epidermis, containing a high concentration of keratinocytes...
Restoration of bone lesions using a bioink based on bone allograft, the latest bioink product of OmidAfarinan Co.
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AllGbone©, the new product of Omidafarinan Co. is a bioink based on extracellular matrix (ECM) of natural bone tissue, which is designed and developed for bone tissue engineering applications. The superiority of this product over the others is its...
Four-dimensional bioprinting
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Four-dimensional (4D) bioprinting, in which the concept of time is integrated with three-dimensional (3D) bioprinting as the fourth dimension, with the goal of constructing complex, functional structures. 4D bioprinting can be used to fabricate dynamic 3D-patterned biological architectures that...
A self-assembling bioink for fabricating vascular-like structures
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Multicomponent self-assembling bioinks offer a unique opportunity to recreate chemical and mechanical features of the ECM and selective communication with cells. Liquid-in-liquid printing, the inoculation of one low viscosity liquid phase into another, offers an opportunity to design bioink...
Bioprinting both bone and soft tissues during surgery simultaneously
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Fixing traumatic injuries to the skin and bones of the face and skull is difficult because of the many layers of different types of tissues involved, but now, researchers have repaired such defects in a rat model using bioprinting...
Manufacturing of the 3D printed COVID-19 rapid test chip (3DcC) by Aerosol Jet nanoparticle 3D printing
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A collaboration led by researchers at Carnegie Mellon University (PA, USA) has reported a COVID-19 antibody detection method created using aerosol jet 3D printing able to report detection within seconds, a breakthrough that could significantly improve studies of vaccine...
Ceramic-based ink to 3D-print bone parts with living cells
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A team of researchers at UNSW (Sydney, Australia) develops a novel, ceramic-based ink to print bone-like structures that harden within minutes of being placed in water. REFERENCE: Romanazzo S, Molley TG, Nemec S et al. Synthetic bone-like structures...
Bioprinted, personalized scaffolds for ankle joint tissue regeneration in development.
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The TRIANKLE consortium made up of 12 European organizations has come together to develop bioprinted, personalized scaffolds for ankle joint tissue regeneration. reference: https://www.3dmednet.com/ https://www.cellink.com/
Bioprinting of cartilage tissue using a 3D bioprinter in the treatment of knee joint injuries
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With the help of bio-3D printing technology, scientists have succeeded in printing 3D cartilage tissue that can easily help those suffering from osteoarthritis or other knee injuries. reference: Costa JB, Park J, Jorgensen AM, Silva-Correia J, Reis RL, Oliveira...
۳D Printing of Bone Grafts for Cleft Alveolar Osteoplasty
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One of the most common hereditary craniofacial anomalies in humans are cleft lip and cleft alveolar bone with or without cleft palate. German researchers developed a novel therapy concept based on 3D printing of biodegradable calcium phosphate-based materials allowing...
Robotic bioprinting platform aims to cure gastric wounds from inside the body
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Gastric wall injury is one of the most common diseases in digestive tract and can lead to surgery if left untreated. Researchers from China’s Tsinghua University have developed a micro bioprinting robot that can treat gastric wounds from inside...
Bioprinting of Beating Heart Tissue with human induced pluripotent stem cells (hiPSCs)
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Researchers at the University of Minnesota (UMN) by developing a new bio-ink were able to bioprint a centimeter-scale heart pump with real human cells. The extracellular matrix (ECM)-based bioink used in this study enabled stem cells to proliferate before differentiation, allowing the team...
Noninvasive in vivo 3D bioprinting
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Despite the extensive advances in 3D bioprinting, its in vivo application has been limited to the cases with exposed traumas (such as burn wounds) or requires a surgical operation. In a recent study by Chinese scientists, the noninvasive in...
Intracorporeal 3D bioprinting using a gelatin-based bioink
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In a collaboration between scientists from the Terasaki Institute for Biomedical Innovation, Ohio State University, and Pennsylvania State University, a gelatin-based bioink has been developed for 3D bioprinting tissue directly in the body. The method used to 3D print...
۳D bioprinting of constructs made of hydrogels and thermoplastic polymers for articular cartilage engineering
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In a national collaboration of Spain scientists, a new bio-ink made of alginate and hyaluronic acid was developed for articular cartilage engineering. To provide the mechanical properties required in cartilage tissue, Polylactic acid was co-printed with the cell-encapsulated hydrogel....
۳D-Printing Responds to Covid-19 Outbreak: A Review on Simple and Feasible Ideas
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With the outbreak of the coronavirus, the daily activities have been significantly disrupted. Therefore, the efforts of many research institutes in the world are focused on combating the spread of the virus. In this session of 3D Bio Club,...