Coaxial 3D printing of hierarchical structured hydrogel scaffolds for repair of spinal cord injury
In vivo evaluation of bone scaffold fabricated by 3D bioprinting method by researchers of OmidAfrinan company
Fabrication of 3D printed hybrid scaffolds carrying dental pulp stem cells
Bioprinting Bone Constructs During Surgery
The beating of the first bioprinted human heart created from stem cells
۳D Bioprinted Multicellular Vascular Models
۳D Printed Punctal Plugs for Controlled Ocular Drug Delivery
۳D Bioprinted Multicellular Vascular Models
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A team of researchers at Texas A&M University (TX, USA) have developed and grown a bioprinted blood vessel able to mimic specific states of health and disease, allowing for the possibility of precision cardiovascular drug advancements. reference: Gold KA,...
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Recently researchers at the National University of Singapore, have been used chitosan methacrylate and PCL as base hydrogel and backing layer respectively to fabricate customizable wound dressings via 3D printing. Synthesized chitosan methacrylate is evaluated to be printable,...
Three-Dimensional Cell Printed Lock-Key Structure for Oral Soft and Hard Tissue Regeneration
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An integrated and heterogeneous soft-hard construct was successfully assembled as a lock-key structure by 3D cell printing. This 3D printed soft-hard construct has the potential to be a customized plug in alveolar ridge preservation. reference: Zhang, S., Li, Q.,...
۳D bio printed spheroid with lobule-like constructs and liver functions
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Recently, Korean researchers presents a method for producing hepatic-lobule-like microtissue spheroids using a bioprinting system and microfluidic emulsification system. A noteworthy point in this study is the use of a precursor cartridge to create a specific pattern in how...
Development of 3D bioprinted GelMA-alginate hydrogels with tunable mechanical properties
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A group of researchers has developed a printed structure composed of GelMA and Alginate bioinks with anisotropic mechanical properties. In this study, it was shown that the mechanical properties of the scaffold can be tunable by creating a striped...
High throughput direct 3D bioprinting (HT-3DP) in multiwell plates
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Researchers at the University of California have developed a high-throughput technique for 3D bioprinting. Their printing method can yield a 96-well plate with tissue samples in each well in as little as 30 minutes. This approach would be useful...
۳d bioprining skin tissues model using primary cells
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In a study by Cellink researchers, a full thickness skin tissue model was bioprinted. In this study, the dermis was bioprinted using primary dermal fibroblasts embedded in GelMA based bioink, and the epidermis, containing a high concentration of keratinocytes...
Restoration of bone lesions using a bioink based on bone allograft, the latest bioink product of OmidAfarinan Co.
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AllGbone©, the new product of Omidafarinan Co. is a bioink based on extracellular matrix (ECM) of natural bone tissue, which is designed and developed for bone tissue engineering applications. The superiority of this product over the others is its...
Four-dimensional bioprinting
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Four-dimensional (4D) bioprinting, in which the concept of time is integrated with three-dimensional (3D) bioprinting as the fourth dimension, with the goal of constructing complex, functional structures. 4D bioprinting can be used to fabricate dynamic 3D-patterned biological architectures that...
Bioprinting both bone and soft tissues during surgery simultaneously
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Fixing traumatic injuries to the skin and bones of the face and skull is difficult because of the many layers of different types of tissues involved, but now, researchers have repaired such defects in a rat model using bioprinting...
Four-axis 3D printing for the fabrication of tubular scaffolds with tailorable mechanical properties
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Researchers developed a four axis extrusion-based additive manufacturing system based on fused deposition modeling (FDM) to create tubular hollow scaffolds. With this technique systematic changes in design can be made to alter the mechanical properties for the targeted tissue...
Genetically-programmed, cell-laden & mechanically strong 3D bioprinted scaffolds for bone repair
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Combined delivery of stem cells with the controlled release of osteogenic factors, within a mechanically-strong biomaterial combined during manufacturing would replace injectable defect fillers (cements) and allow personalized implants to be rapidly prototyped by 3D bioprinting. To this end,...
An in-vitro liver model using 3D bioprinting core–shell structure of hepatocytes and fibroblasts
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With the aim of understanding cellular interactions of hepatocytes in their physiological microenvironment and to generate an artificial 3D in vitro model of liver, a co-culture system using 3D extrusion bioprinting was developed. In this method, bio-ink based on...
The first 3D-printable ‘bottlebrush’ elastomer
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Researchers have developed the first 3D-printable ‘bottlebrush’ elastomer. The new material results in printed objects that have unusual softness, elasticity and mechanical properties that closely resemble those of human tissue. Unique molecular structure of bottlebrush elastomers facilitate bioprinting in...
Manufacturing of the 3D printed COVID-19 rapid test chip (3DcC) by Aerosol Jet nanoparticle 3D printing
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A collaboration led by researchers at Carnegie Mellon University (PA, USA) has reported a COVID-19 antibody detection method created using aerosol jet 3D printing able to report detection within seconds, a breakthrough that could significantly improve studies of vaccine...
Ceramic-based ink to 3D-print bone parts with living cells
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A team of researchers at UNSW (Sydney, Australia) develops a novel, ceramic-based ink to print bone-like structures that harden within minutes of being placed in water. REFERENCE: Romanazzo S, Molley TG, Nemec S et al. Synthetic bone-like structures...
۳D Bioprinted Alginate patches for cardiovascular disease
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A team of Iranian researchers used a novel technique to print sodium alginate cardiac patches using OmidAfarinan bioprinters. The results indicated that the prepared patch can be a suitable candidate for treating the cardiac scars after cardiovascular disease. reference:...
Bioprinted, personalized scaffolds for ankle joint tissue regeneration in development.
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The TRIANKLE consortium made up of 12 European organizations has come together to develop bioprinted, personalized scaffolds for ankle joint tissue regeneration. reference: https://www.3dmednet.com/ https://www.cellink.com/
۳D bioprinting of anisotropic engineered tissue constructs with ultrasonically induced cell patterning
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US researchers have developed a new bioprinting technique that uses ultrasonic standing bulk acoustic waves (SBAW) to organize cells into controllable anisotropic patterns within viscous bioinks while maintaining high cell viability. This work represents a step forward in advancing...
Fabrication of Three-Dimensional Composite Scaffold for Simultaneous Alveolar Bone Regeneration in Dental Implant Installation
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Korean researchers have designed a 3D printed composite scaffold that can be combined simultaneously with bone grafts and fixtures to minimize the cost and duration of dental implant surgery. Further, by using 3D printing technology in making this implant,...
Mini-kidneys bioprinted for toxicology research and treatment developments
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A team of Australian researchers apply extrusion-based three-dimensional cellular bioprinting to deliver rapid and high-throughput generation of kidney organoids with highly reproducible cell number and viability. Automated extrusion-based bioprinting for kidney organoid production delivers improvements in throughput, quality control,...
Evaluation of the effects of cell-dispensing using an inkjet-based bioprinter on cell integrity
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Japanese researchers have developed a stress-free and media-direct-dispensing inkjet bioprinter that exhibited cell-friendly dispensing performance, which was similar to the manual dispensing operation, based not only on cell viability but also on gene expression levels. reference: https://www.nature.com/articles/s41598-020-64193-z Yumoto M,...
Bioprinting of cartilage tissue using a 3D bioprinter in the treatment of knee joint injuries
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With the help of bio-3D printing technology, scientists have succeeded in printing 3D cartilage tissue that can easily help those suffering from osteoarthritis or other knee injuries. reference: Costa JB, Park J, Jorgensen AM, Silva-Correia J, Reis RL, Oliveira...
Vascularized cell-laden 3D bioprinted wound dressings for regenerative medicine applications
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Using three-dimensional printed structures with vascular networks is considered as a novel cell-based therapy for regenerative medicine applications. A team of researchers at the University of Otago (New Zealand) reports a promising strategy using core shell extrusion 3D bioprinting...