Coaxial 3D printing of hierarchical structured hydrogel scaffolds for repair of spinal cord injury
In vivo evaluation of bone scaffold fabricated by 3D bioprinting method by researchers of OmidAfrinan company
Fabrication of 3D printed hybrid scaffolds carrying dental pulp stem cells
Bioprinting Bone Constructs During Surgery
The beating of the first bioprinted human heart created from stem cells
۳D Bioprinted Multicellular Vascular Models
۳D Printed Punctal Plugs for Controlled Ocular Drug Delivery
۳D Printed Punctal Plugs for Controlled Ocular Drug Delivery
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Researchers have used the digital light processing (DLP) printing technique to develop dexamethasone-loaded punctal plugs. In this study, dexamethasone was used as an anti-inflammatory steroid drug in the treatment of corneal diseases. Punctal plugs with different drug loadings were...
An in-vitro liver model using 3D bioprinting core–shell structure of hepatocytes and fibroblasts
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With the aim of understanding cellular interactions of hepatocytes in their physiological microenvironment and to generate an artificial 3D in vitro model of liver, a co-culture system using 3D extrusion bioprinting was developed. In this method, bio-ink based on...
The first 3D-printable ‘bottlebrush’ elastomer
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Researchers have developed the first 3D-printable ‘bottlebrush’ elastomer. The new material results in printed objects that have unusual softness, elasticity and mechanical properties that closely resemble those of human tissue. Unique molecular structure of bottlebrush elastomers facilitate bioprinting in...
Manufacturing of the 3D printed COVID-19 rapid test chip (3DcC) by Aerosol Jet nanoparticle 3D printing
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A collaboration led by researchers at Carnegie Mellon University (PA, USA) has reported a COVID-19 antibody detection method created using aerosol jet 3D printing able to report detection within seconds, a breakthrough that could significantly improve studies of vaccine...
Ceramic-based ink to 3D-print bone parts with living cells
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A team of researchers at UNSW (Sydney, Australia) develops a novel, ceramic-based ink to print bone-like structures that harden within minutes of being placed in water. REFERENCE: Romanazzo S, Molley TG, Nemec S et al. Synthetic bone-like structures...
۳D Bioprinted Alginate patches for cardiovascular disease
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A team of Iranian researchers used a novel technique to print sodium alginate cardiac patches using OmidAfarinan bioprinters. The results indicated that the prepared patch can be a suitable candidate for treating the cardiac scars after cardiovascular disease. reference:...
Bioprinted, personalized scaffolds for ankle joint tissue regeneration in development.
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The TRIANKLE consortium made up of 12 European organizations has come together to develop bioprinted, personalized scaffolds for ankle joint tissue regeneration. reference: https://www.3dmednet.com/ https://www.cellink.com/
۳D bioprinting of anisotropic engineered tissue constructs with ultrasonically induced cell patterning
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US researchers have developed a new bioprinting technique that uses ultrasonic standing bulk acoustic waves (SBAW) to organize cells into controllable anisotropic patterns within viscous bioinks while maintaining high cell viability. This work represents a step forward in advancing...
Fabrication of Three-Dimensional Composite Scaffold for Simultaneous Alveolar Bone Regeneration in Dental Implant Installation
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Korean researchers have designed a 3D printed composite scaffold that can be combined simultaneously with bone grafts and fixtures to minimize the cost and duration of dental implant surgery. Further, by using 3D printing technology in making this implant,...
Mini-kidneys bioprinted for toxicology research and treatment developments
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A team of Australian researchers apply extrusion-based three-dimensional cellular bioprinting to deliver rapid and high-throughput generation of kidney organoids with highly reproducible cell number and viability. Automated extrusion-based bioprinting for kidney organoid production delivers improvements in throughput, quality control,...
Evaluation of the effects of cell-dispensing using an inkjet-based bioprinter on cell integrity
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Japanese researchers have developed a stress-free and media-direct-dispensing inkjet bioprinter that exhibited cell-friendly dispensing performance, which was similar to the manual dispensing operation, based not only on cell viability but also on gene expression levels. reference: https://www.nature.com/articles/s41598-020-64193-z Yumoto M,...
Bioprinting of cartilage tissue using a 3D bioprinter in the treatment of knee joint injuries
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With the help of bio-3D printing technology, scientists have succeeded in printing 3D cartilage tissue that can easily help those suffering from osteoarthritis or other knee injuries. reference: Costa JB, Park J, Jorgensen AM, Silva-Correia J, Reis RL, Oliveira...
۳D Printing of Bone Grafts for Cleft Alveolar Osteoplasty
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One of the most common hereditary craniofacial anomalies in humans are cleft lip and cleft alveolar bone with or without cleft palate. German researchers developed a novel therapy concept based on 3D printing of biodegradable calcium phosphate-based materials allowing...
Enhancement of 3D cell printing by using silk nanofibers
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In a study recently published in Materials Today Bio, researchers from Osaka University have used silk nanofibers obtained by mechanical disintegration to enhance the printing process without damaging the cells or cell assemblies. reference: https://www.3dmednet.com/silk-fibers-provide-integrity-and-prevent-cell-damage-in-3d-printed-biological-constructs/ Sakai S, Yoshii A,...
Novel bioink for 4D bioprinting tissue-mimicking materials
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A team of researchers from Linköping University (Sweden) has developed a modular and 3D printable hyaluronan-based hydrogels to keep cells alive throughout the printing process. reference Aronsson, C., Jury, M., Naeimipour, S., Boroojeni, F. R., Christoffersson, J., Lifwergren, P.,...
۳D-printed capsule could collect bacteria from throughout the gastrointestinal tract
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A novel 3D-printed capsule, developed by a team at Purdue University (IL, USA), could allow for the collection of bacteria samples from throughout the gastrointestinal tract, improving on conventional sampling methods that may exclude areas for bacteria collection outside...
Bioprinting of Beating Heart Tissue with human induced pluripotent stem cells (hiPSCs)
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Researchers at the University of Minnesota (UMN) by developing a new bio-ink were able to bioprint a centimeter-scale heart pump with real human cells. The extracellular matrix (ECM)-based bioink used in this study enabled stem cells to proliferate before differentiation, allowing the team...
Noninvasive in vivo 3D bioprinting
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Despite the extensive advances in 3D bioprinting, its in vivo application has been limited to the cases with exposed traumas (such as burn wounds) or requires a surgical operation. In a recent study by Chinese scientists, the noninvasive in...
Oxygen Generating Bioinks: An Approach Providing Oxygen to Cells Encapsulated in Non Vasculirized Grafts
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Of the main challenges against the translation of tissue-engineered grafts is the lack of enough oxygen in thick tissues known as hypoxia. Interestingly, there is a category of materials that generate oxygen. In a recent study, a bioink of...
Intravital three dimensional bioprinting
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A group of researchers from the University College London and the University of Padua (Italy) unveiled a minimally invasive 3D bioprinting technique that can be used for the fabrication of 3D constructs across and within tissues. This study results,...
Intracorporeal 3D bioprinting using a gelatin-based bioink
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In a collaboration between scientists from the Terasaki Institute for Biomedical Innovation, Ohio State University, and Pennsylvania State University, a gelatin-based bioink has been developed for 3D bioprinting tissue directly in the body. The method used to 3D print...
The First 3D Bioprinting Experiment In Space Is Achieved
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In a collaboration between the Geneva Foundation (Geneva), the Uniformed Services University of the Health Sciences (USU), commercial space company TechShot, Inc, and 3D printer manufacturer nScrypt, Inc, the first bioprinting project in space about the engineering of the...
۳D bioprinting of constructs made of hydrogels and thermoplastic polymers for articular cartilage engineering
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In a national collaboration of Spain scientists, a new bio-ink made of alginate and hyaluronic acid was developed for articular cartilage engineering. To provide the mechanical properties required in cartilage tissue, Polylactic acid was co-printed with the cell-encapsulated hydrogel....
۳D-Printing Responds to Covid-19 Outbreak: A Review on Simple and Feasible Ideas
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With the outbreak of the coronavirus, the daily activities have been significantly disrupted. Therefore, the efforts of many research institutes in the world are focused on combating the spread of the virus. In this session of 3D Bio Club,...