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تصویر: ۳D Bioprinted Multicellular Vascular Models

۳D Bioprinted Multicellular Vascular Models

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A team of researchers at Texas A&M University (TX, USA) have developed and grown a bioprinted blood vessel able to mimic specific states of health and disease, allowing for the possibility of precision cardiovascular drug advancements. reference: Gold KA,...

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  Recently researchers at the National University of Singapore, have been used chitosan methacrylate and PCL as base hydrogel and backing layer respectively to fabricate customizable wound dressings via 3D printing. Synthesized chitosan methacrylate is evaluated to be printable,...

تصویر: Four-axis 3D printing for the fabrication of tubular scaffolds with tailorable mechanical properties

Four-axis 3D printing for the fabrication of tubular scaffolds with tailorable mechanical properties

Researchers developed a four axis extrusion-based additive manufacturing system based on fused deposition modeling (FDM) to create tubular hollow scaffolds. With this technique systematic changes in design can be made to alter the mechanical properties for the targeted tissue...

تصویر: An in-vitro liver model using 3D bioprinting core–shell structure of hepatocytes and fibroblasts

An in-vitro liver model using 3D bioprinting core–shell structure of hepatocytes and fibroblasts

With the aim of understanding cellular interactions of hepatocytes in their physiological microenvironment and to generate an artificial 3D in vitro model of liver, a co-culture system using 3D extrusion bioprinting was developed. In this method, bio-ink based on...

تصویر: The first 3D-printable ‘bottlebrush’ elastomer

The first 3D-printable ‘bottlebrush’ elastomer

Researchers have developed the first 3D-printable ‘bottlebrush’ elastomer. The new material results in printed objects that have unusual softness, elasticity and mechanical properties that closely resemble those of human tissue. Unique molecular structure of bottlebrush elastomers facilitate bioprinting in...

تصویر: Ceramic-based ink to 3D-print bone parts with living cells

Ceramic-based ink to 3D-print bone parts with living cells

A team of researchers at UNSW (Sydney, Australia) develops a novel, ceramic-based ink to print bone-like structures that harden within minutes of being placed in water.   REFERENCE: Romanazzo S, Molley TG, Nemec S et al. Synthetic bone-like structures...

تصویر: ۳D Bioprinted Alginate patches for cardiovascular disease

۳D Bioprinted Alginate patches for cardiovascular disease

A team of Iranian researchers used a novel technique to print sodium alginate cardiac patches using OmidAfarinan bioprinters. The results indicated that the prepared patch can be a suitable candidate for treating the cardiac scars after cardiovascular disease. reference:...

تصویر: Bioprinted, personalized scaffolds for ankle joint tissue regeneration in development.

Bioprinted, personalized scaffolds for ankle joint tissue regeneration in development.

The TRIANKLE consortium made up of 12 European organizations has come together to develop bioprinted, personalized scaffolds for ankle joint tissue regeneration.   reference: https://www.3dmednet.com/ https://www.cellink.com/

تصویر: Nucleotide lipid-based hydrogel as a new route to produce crosslinker-free scaffolds

Nucleotide lipid-based hydrogel as a new route to produce crosslinker-free scaffolds

Despite recent advances in tissue engineering and biofabrication, progress has been limited to the development of bioinks based on polymers.  Scientist show that a nucleotide lipid-based hydrogel resulting from the self-assembly of nucleotide lipids can be used as a...

تصویر: ۳D bioprinting of anisotropic engineered tissue constructs with ultrasonically induced cell patterning

۳D bioprinting of anisotropic engineered tissue constructs with ultrasonically induced cell patterning

US researchers have developed a new bioprinting technique that uses ultrasonic standing bulk acoustic waves (SBAW) to organize cells into controllable anisotropic patterns within viscous bioinks while maintaining high cell viability. This work represents a step forward in advancing...

تصویر: Fabrication of Three-Dimensional Composite Scaffold for Simultaneous Alveolar Bone Regeneration in Dental Implant Installation

Fabrication of Three-Dimensional Composite Scaffold for Simultaneous Alveolar Bone Regeneration in Dental Implant Installation

Korean researchers have designed a 3D printed composite scaffold that can be combined simultaneously with bone grafts and fixtures to minimize the cost and duration of dental implant surgery. Further, by using 3D printing technology in making this implant,...

تصویر: Mini-kidneys bioprinted for toxicology research and treatment developments

Mini-kidneys bioprinted for toxicology research and treatment developments

A team of Australian researchers apply extrusion-based three-dimensional cellular bioprinting to deliver rapid and high-throughput generation of kidney organoids with highly reproducible cell number and viability. Automated extrusion-based bioprinting for kidney organoid production delivers improvements in throughput, quality control,...

تصویر: Evaluation of the effects of cell-dispensing using an inkjet-based bioprinter on cell integrity

Evaluation of the effects of cell-dispensing using an inkjet-based bioprinter on cell integrity

Japanese researchers have developed a stress-free and media-direct-dispensing inkjet bioprinter that exhibited cell-friendly dispensing performance, which was similar to the manual dispensing operation, based not only on cell viability but also on gene expression levels. reference: https://www.nature.com/articles/s41598-020-64193-z Yumoto M,...

تصویر: Bioprinting of cartilage tissue using a 3D bioprinter in the treatment of knee joint injuries

Bioprinting of cartilage tissue using a 3D bioprinter in the treatment of knee joint injuries

With the help of bio-3D printing technology, scientists have succeeded in printing 3D cartilage tissue that can easily help those suffering from osteoarthritis or other knee injuries. reference: Costa JB, Park J, Jorgensen AM, Silva-Correia J, Reis RL, Oliveira...

تصویر: Vascularized cell-laden 3D bioprinted wound dressings for regenerative medicine applications

Vascularized cell-laden 3D bioprinted wound dressings for regenerative medicine applications

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Using three-dimensional printed structures with vascular networks is considered as a novel cell-based therapy for regenerative medicine applications. A team of researchers at the University of Otago (New Zealand) reports a promising strategy using core shell extrusion 3D bioprinting...

تصویر: ۳D Printing of Bone Grafts for Cleft Alveolar Osteoplasty

۳D Printing of Bone Grafts for Cleft Alveolar Osteoplasty

One of the most common hereditary craniofacial anomalies in humans are cleft lip and cleft alveolar bone with or without cleft palate. German researchers developed a novel therapy concept based on 3D printing of biodegradable calcium phosphate-based materials allowing...

تصویر: Enhancement of 3D cell printing by using silk nanofibers

Enhancement of 3D cell printing by using silk nanofibers

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In a study recently published in Materials Today Bio, researchers from Osaka University have used silk nanofibers obtained by mechanical disintegration to enhance the printing process without damaging the cells or cell assemblies. reference: https://www.3dmednet.com/silk-fibers-provide-integrity-and-prevent-cell-damage-in-3d-printed-biological-constructs/ Sakai S, Yoshii A,...

تصویر: Novel bioink for 4D bioprinting tissue-mimicking materials

Novel bioink for 4D bioprinting tissue-mimicking materials

A team of researchers from Linköping University (Sweden) has developed a modular and 3D printable hyaluronan-based hydrogels to keep cells alive throughout the printing process. reference Aronsson, C., Jury, M., Naeimipour, S., Boroojeni, F. R., Christoffersson, J., Lifwergren, P.,...

تصویر: Novel bioprinting platform supports bone regeneration

Novel bioprinting platform supports bone regeneration

A collaborative team from the SFI Research Centre for Advanced Materials and Bioengineering Research (AMBER; Dublin, Republic of Ireland) and the Trinity Centre for Biomedical Engineering at Trinity College Dublin (Republic of Ireland) has developed a novel bioprinting platform...

تصویر: Robotic bioprinting platform aims to cure gastric wounds from inside the body

Robotic bioprinting platform aims to cure gastric wounds from inside the body

Gastric wall injury is one of the most common diseases in digestive tract and can lead to surgery if left untreated. Researchers from China’s Tsinghua University have developed a micro bioprinting robot that can treat gastric wounds from inside...

تصویر: ۳D-printed patches for long term release of drugs to treat myocardial infarction

۳D-printed patches for long term release of drugs to treat myocardial infarction

Up to now, many methods have been presented to treat cardiovascular diseases as the first cause of human death worldwide. In a recent study by Finish scientists, multifunctional patches presenting suitable biocompatibility, electrical conductivity, and mechanical strength have been...

تصویر: Oxygen Generating Bioinks: An Approach Providing Oxygen to Cells Encapsulated in Non Vasculirized Grafts

Oxygen Generating Bioinks: An Approach Providing Oxygen to Cells Encapsulated in Non Vasculirized Grafts

Of the main challenges against the translation of tissue-engineered grafts is the lack of enough oxygen in thick tissues known as hypoxia. Interestingly, there is a category of materials that generate oxygen. In a recent study, a bioink of...

تصویر: Intravital three dimensional bioprinting

Intravital three dimensional bioprinting

A group of researchers from the University College London and the University of Padua (Italy) unveiled a minimally invasive 3D bioprinting technique that can be used for the fabrication of 3D constructs across and within tissues. This study results,...

تصویر: Intracorporeal 3D bioprinting using a gelatin-based bioink

Intracorporeal 3D bioprinting using a gelatin-based bioink

In a collaboration between scientists from the Terasaki Institute for Biomedical Innovation, Ohio State University, and Pennsylvania State University, a gelatin-based bioink has been developed for 3D bioprinting tissue directly in the body. The method used to 3D print...