Coaxial 3D printing of hierarchical structured hydrogel scaffolds for repair of spinal cord injury
In vivo evaluation of bone scaffold fabricated by 3D bioprinting method by researchers of OmidAfrinan company
Fabrication of 3D printed hybrid scaffolds carrying dental pulp stem cells
Bioprinting Bone Constructs During Surgery
The beating of the first bioprinted human heart created from stem cells
۳D Bioprinted Multicellular Vascular Models
۳D Printed Punctal Plugs for Controlled Ocular Drug Delivery
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Recently researchers at the National University of Singapore, have been used chitosan methacrylate and PCL as base hydrogel and backing layer respectively to fabricate customizable wound dressings via 3D printing. Synthesized chitosan methacrylate is evaluated to be printable,...
High throughput direct 3D bioprinting (HT-3DP) in multiwell plates
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Researchers at the University of California have developed a high-throughput technique for 3D bioprinting. Their printing method can yield a 96-well plate with tissue samples in each well in as little as 30 minutes. This approach would be useful...
Restoration of bone lesions using a bioink based on bone allograft, the latest bioink product of OmidAfarinan Co.
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AllGbone©, the new product of Omidafarinan Co. is a bioink based on extracellular matrix (ECM) of natural bone tissue, which is designed and developed for bone tissue engineering applications. The superiority of this product over the others is its...
Bioprinting both bone and soft tissues during surgery simultaneously
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Fixing traumatic injuries to the skin and bones of the face and skull is difficult because of the many layers of different types of tissues involved, but now, researchers have repaired such defects in a rat model using bioprinting...
Serpooshan Awarded NSF CAREER Award to Bioprint a 3D Model of the Developing Human Heart
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Serpooshan Awarded NSF CAREER Award to Bioprint a 3D Model of the Developing Human Heart. The project focuses on understanding normal heart development and what can go wrong in those processes and lead to severe defects. reference: https://bme.gatech.edu/bme/serpooshan-awarded-nsf-career-award-bioprint-3d-model-developing-human-heart
Genetically-programmed, cell-laden & mechanically strong 3D bioprinted scaffolds for bone repair
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Combined delivery of stem cells with the controlled release of osteogenic factors, within a mechanically-strong biomaterial combined during manufacturing would replace injectable defect fillers (cements) and allow personalized implants to be rapidly prototyped by 3D bioprinting. To this end,...
An in-vitro liver model using 3D bioprinting core–shell structure of hepatocytes and fibroblasts
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With the aim of understanding cellular interactions of hepatocytes in their physiological microenvironment and to generate an artificial 3D in vitro model of liver, a co-culture system using 3D extrusion bioprinting was developed. In this method, bio-ink based on...
The first 3D-printable ‘bottlebrush’ elastomer
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Researchers have developed the first 3D-printable ‘bottlebrush’ elastomer. The new material results in printed objects that have unusual softness, elasticity and mechanical properties that closely resemble those of human tissue. Unique molecular structure of bottlebrush elastomers facilitate bioprinting in...
Ceramic-based ink to 3D-print bone parts with living cells
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A team of researchers at UNSW (Sydney, Australia) develops a novel, ceramic-based ink to print bone-like structures that harden within minutes of being placed in water. REFERENCE: Romanazzo S, Molley TG, Nemec S et al. Synthetic bone-like structures...
Nucleotide lipid-based hydrogel as a new route to produce crosslinker-free scaffolds
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Despite recent advances in tissue engineering and biofabrication, progress has been limited to the development of bioinks based on polymers. Scientist show that a nucleotide lipid-based hydrogel resulting from the self-assembly of nucleotide lipids can be used as a...
Fabrication of Three-Dimensional Composite Scaffold for Simultaneous Alveolar Bone Regeneration in Dental Implant Installation
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Korean researchers have designed a 3D printed composite scaffold that can be combined simultaneously with bone grafts and fixtures to minimize the cost and duration of dental implant surgery. Further, by using 3D printing technology in making this implant,...
Bioprinting of cartilage tissue using a 3D bioprinter in the treatment of knee joint injuries
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With the help of bio-3D printing technology, scientists have succeeded in printing 3D cartilage tissue that can easily help those suffering from osteoarthritis or other knee injuries. reference: Costa JB, Park J, Jorgensen AM, Silva-Correia J, Reis RL, Oliveira...
۳D Printing of Bone Grafts for Cleft Alveolar Osteoplasty
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One of the most common hereditary craniofacial anomalies in humans are cleft lip and cleft alveolar bone with or without cleft palate. German researchers developed a novel therapy concept based on 3D printing of biodegradable calcium phosphate-based materials allowing...
Using spheroid bioprinting to accelerate research on anti-COVID-19 drugs
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To accelerate the transition from preclinical studies with laboratory animals to clinical studies with humans, specialists at the biotechnological research laboratory ۳D Bioprinting Solutions (۳DBio) developed a method for the scalable production of 3D spheroids in the quantities necessary to...
Enhancement of 3D cell printing by using silk nanofibers
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In a study recently published in Materials Today Bio, researchers from Osaka University have used silk nanofibers obtained by mechanical disintegration to enhance the printing process without damaging the cells or cell assemblies. reference: https://www.3dmednet.com/silk-fibers-provide-integrity-and-prevent-cell-damage-in-3d-printed-biological-constructs/ Sakai S, Yoshii A,...
Bioprinting and computer modeling facilitates study of cancer spread in blood vessels.
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A team of scientists from the Lawrence Livermore National Laboratory (CA, USA) has used bioprinted, living brain vasculature models in tandem with computer modeling simulations to provide insights on why cancer cells metastasize in certain areas of the vasculature....
Novel bioink for 4D bioprinting tissue-mimicking materials
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A team of researchers from Linköping University (Sweden) has developed a modular and 3D printable hyaluronan-based hydrogels to keep cells alive throughout the printing process. reference Aronsson, C., Jury, M., Naeimipour, S., Boroojeni, F. R., Christoffersson, J., Lifwergren, P.,...
۳D-printed capsule could collect bacteria from throughout the gastrointestinal tract
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A novel 3D-printed capsule, developed by a team at Purdue University (IL, USA), could allow for the collection of bacteria samples from throughout the gastrointestinal tract, improving on conventional sampling methods that may exclude areas for bacteria collection outside...
Novel bioprinting platform supports bone regeneration
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A collaborative team from the SFI Research Centre for Advanced Materials and Bioengineering Research (AMBER; Dublin, Republic of Ireland) and the Trinity Centre for Biomedical Engineering at Trinity College Dublin (Republic of Ireland) has developed a novel bioprinting platform...
Bioprinting of Beating Heart Tissue with human induced pluripotent stem cells (hiPSCs)
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Researchers at the University of Minnesota (UMN) by developing a new bio-ink were able to bioprint a centimeter-scale heart pump with real human cells. The extracellular matrix (ECM)-based bioink used in this study enabled stem cells to proliferate before differentiation, allowing the team...
Noninvasive in vivo 3D bioprinting
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Despite the extensive advances in 3D bioprinting, its in vivo application has been limited to the cases with exposed traumas (such as burn wounds) or requires a surgical operation. In a recent study by Chinese scientists, the noninvasive in...
Oxygen Generating Bioinks: An Approach Providing Oxygen to Cells Encapsulated in Non Vasculirized Grafts
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Of the main challenges against the translation of tissue-engineered grafts is the lack of enough oxygen in thick tissues known as hypoxia. Interestingly, there is a category of materials that generate oxygen. In a recent study, a bioink of...