Designing patient-specific bone grafts by 3D-bioprinting technology has gathered a great deal of attention from researchers and clinicians. In this vein, a research group at Texas A&M University has developed an advanced bioink known as Nanoengineered Ionic–Covalent Entanglement (NICE) bioink. This nano-reinforced bioink benefits from ionic and covalent crosslinking and presents suitable physical and biological properties for bioprinting of anatomical-scale functional bone tissues.
