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  Recently researchers at the National University of Singapore, have been used chitosan methacrylate and PCL as base hydrogel and backing layer respectively to fabricate customizable wound dressings via 3D printing. Synthesized chitosan methacrylate is evaluated to be printable,...

تصویر: ۳D Printed Punctal Plugs for Controlled Ocular Drug Delivery

۳D Printed Punctal Plugs for Controlled Ocular Drug Delivery

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Researchers have used the digital light processing (DLP) printing technique to develop dexamethasone-loaded punctal plugs. In this study, dexamethasone was used as an anti-inflammatory steroid drug in the treatment of corneal diseases. Punctal plugs with different drug loadings were...

تصویر: ۳D bio printed spheroid with lobule-like constructs and liver functions

۳D bio printed spheroid with lobule-like constructs and liver functions

Recently, Korean researchers presents a method for producing hepatic-lobule-like microtissue spheroids using a bioprinting system and microfluidic emulsification system.  A noteworthy point in this study is the use of a precursor cartridge to create a specific pattern in how...

تصویر: ۳d bioprining skin tissues model using primary cells

۳d bioprining skin tissues model using primary cells

In a study by Cellink researchers, a full thickness skin tissue model was bioprinted. In this study, the dermis was bioprinted using primary dermal fibroblasts embedded in GelMA based bioink, and the epidermis, containing a high concentration of keratinocytes...

تصویر: Four-dimensional bioprinting

Four-dimensional bioprinting

Four-dimensional (4D) bioprinting, in which the concept of time is integrated with three-dimensional (3D) bioprinting as the fourth dimension, with the goal of constructing complex, functional structures. 4D bioprinting can be used to fabricate dynamic 3D-patterned biological architectures that...

تصویر: Bioprinting both bone and soft tissues during surgery simultaneously

Bioprinting both bone and soft tissues during surgery simultaneously

Fixing traumatic injuries to the skin and bones of the face and skull is difficult because of the many layers of different types of tissues involved, but now, researchers have repaired such defects in a rat model using bioprinting...

تصویر: Serpooshan Awarded NSF CAREER Award to Bioprint a 3D Model of the Developing Human Heart

Serpooshan Awarded NSF CAREER Award to Bioprint a 3D Model of the Developing Human Heart

Serpooshan Awarded NSF CAREER Award to Bioprint a 3D Model of the Developing Human Heart. The project focuses on understanding normal heart development and what can go wrong in those processes and lead to severe defects. reference: https://bme.gatech.edu/bme/serpooshan-awarded-nsf-career-award-bioprint-3d-model-developing-human-heart

تصویر: The first 3D-printable ‘bottlebrush’ elastomer

The first 3D-printable ‘bottlebrush’ elastomer

Researchers have developed the first 3D-printable ‘bottlebrush’ elastomer. The new material results in printed objects that have unusual softness, elasticity and mechanical properties that closely resemble those of human tissue. Unique molecular structure of bottlebrush elastomers facilitate bioprinting in...

تصویر: ۳D Bioprinted Alginate patches for cardiovascular disease

۳D Bioprinted Alginate patches for cardiovascular disease

A team of Iranian researchers used a novel technique to print sodium alginate cardiac patches using OmidAfarinan bioprinters. The results indicated that the prepared patch can be a suitable candidate for treating the cardiac scars after cardiovascular disease. reference:...

تصویر: ۳D bioprinting of anisotropic engineered tissue constructs with ultrasonically induced cell patterning

۳D bioprinting of anisotropic engineered tissue constructs with ultrasonically induced cell patterning

US researchers have developed a new bioprinting technique that uses ultrasonic standing bulk acoustic waves (SBAW) to organize cells into controllable anisotropic patterns within viscous bioinks while maintaining high cell viability. This work represents a step forward in advancing...

تصویر: Fabrication of Three-Dimensional Composite Scaffold for Simultaneous Alveolar Bone Regeneration in Dental Implant Installation

Fabrication of Three-Dimensional Composite Scaffold for Simultaneous Alveolar Bone Regeneration in Dental Implant Installation

Korean researchers have designed a 3D printed composite scaffold that can be combined simultaneously with bone grafts and fixtures to minimize the cost and duration of dental implant surgery. Further, by using 3D printing technology in making this implant,...

تصویر: Mini-kidneys bioprinted for toxicology research and treatment developments

Mini-kidneys bioprinted for toxicology research and treatment developments

A team of Australian researchers apply extrusion-based three-dimensional cellular bioprinting to deliver rapid and high-throughput generation of kidney organoids with highly reproducible cell number and viability. Automated extrusion-based bioprinting for kidney organoid production delivers improvements in throughput, quality control,...

تصویر: Evaluation of the effects of cell-dispensing using an inkjet-based bioprinter on cell integrity

Evaluation of the effects of cell-dispensing using an inkjet-based bioprinter on cell integrity

Japanese researchers have developed a stress-free and media-direct-dispensing inkjet bioprinter that exhibited cell-friendly dispensing performance, which was similar to the manual dispensing operation, based not only on cell viability but also on gene expression levels. reference: https://www.nature.com/articles/s41598-020-64193-z Yumoto M,...

تصویر: Vascularized cell-laden 3D bioprinted wound dressings for regenerative medicine applications

Vascularized cell-laden 3D bioprinted wound dressings for regenerative medicine applications

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Using three-dimensional printed structures with vascular networks is considered as a novel cell-based therapy for regenerative medicine applications. A team of researchers at the University of Otago (New Zealand) reports a promising strategy using core shell extrusion 3D bioprinting...

تصویر: Enhancement of 3D cell printing by using silk nanofibers

Enhancement of 3D cell printing by using silk nanofibers

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In a study recently published in Materials Today Bio, researchers from Osaka University have used silk nanofibers obtained by mechanical disintegration to enhance the printing process without damaging the cells or cell assemblies. reference: https://www.3dmednet.com/silk-fibers-provide-integrity-and-prevent-cell-damage-in-3d-printed-biological-constructs/ Sakai S, Yoshii A,...

تصویر: Bioprinting and computer modeling facilitates study of cancer spread in blood vessels.

Bioprinting and computer modeling facilitates study of cancer spread in blood vessels.

A team of scientists from the Lawrence Livermore National Laboratory (CA, USA) has used bioprinted, living brain vasculature models in tandem with computer modeling simulations to provide insights on why cancer cells metastasize in certain areas of the vasculature....

تصویر: ۳D-printed capsule could collect bacteria from throughout the gastrointestinal tract

۳D-printed capsule could collect bacteria from throughout the gastrointestinal tract

A novel 3D-printed capsule, developed by a team at Purdue University (IL, USA), could allow for the collection of bacteria samples from throughout the gastrointestinal tract, improving on conventional sampling methods that may exclude areas for bacteria collection outside...

تصویر: Novel bioprinting platform supports bone regeneration

Novel bioprinting platform supports bone regeneration

A collaborative team from the SFI Research Centre for Advanced Materials and Bioengineering Research (AMBER; Dublin, Republic of Ireland) and the Trinity Centre for Biomedical Engineering at Trinity College Dublin (Republic of Ireland) has developed a novel bioprinting platform...

تصویر: Bioprinting of Beating Heart Tissue with human induced pluripotent stem cells (hiPSCs)

Bioprinting of Beating Heart Tissue with human induced pluripotent stem cells (hiPSCs)

Researchers at the University of Minnesota (UMN) by developing a new bio-ink were able to bioprint a centimeter-scale heart pump with real human cells. The extracellular matrix (ECM)-based bioink used in this study enabled stem cells to proliferate before differentiation, allowing the team...

تصویر: The First 3D Bioprinting Experiment In Space Is Achieved

The First 3D Bioprinting Experiment In Space Is Achieved

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In a collaboration between the Geneva Foundation (Geneva), the Uniformed Services University of the Health Sciences (USU), commercial space company TechShot, Inc, and 3D printer manufacturer nScrypt, Inc, the first bioprinting project in space about the engineering of the...

تصویر: ۳D bioprinting of constructs made of hydrogels and thermoplastic polymers for articular cartilage engineering

۳D bioprinting of constructs made of hydrogels and thermoplastic polymers for articular cartilage engineering

In a national collaboration of Spain scientists, a new bio-ink made of alginate and hyaluronic acid was developed for articular cartilage engineering. To provide the mechanical properties required in cartilage tissue, Polylactic acid was co-printed with the cell-encapsulated hydrogel....

تصویر: ۳D-Printing Responds to Covid-19 Outbreak: A Review on Simple and Feasible Ideas

۳D-Printing Responds to Covid-19 Outbreak: A Review on Simple and Feasible Ideas

With the outbreak of the coronavirus, the daily activities have been significantly disrupted. Therefore, the efforts of many research institutes in the world are focused on combating the spread of the virus. In this session of 3D Bio Club,...

تصویر: Priming mesenchymal stem cells in vivo: A game-changer to treat myocardial infarction induced hearts

Priming mesenchymal stem cells in vivo: A game-changer to treat myocardial infarction induced hearts

Despite the great potential of mesenchymal stem cells in various regeneration therapies, their application to treat myocardial infarction (MI)–induced hearts is limited. In  recent research by an international joint research team of POSTECH, Seoul St. Mary’s Hospital, and City...

تصویر: Development of functional scaffolds for bone tissue engineering using 3D-bioprinting

Development of functional scaffolds for bone tissue engineering using 3D-bioprinting

Extrusion-based 3D-printing is among the additive manufacturing (AM) techniques that have attracted much attention for the fabrication of bone tissue engineering scaffolds with defined geometries and internal structure. The aim of the studies performed in this thesis was to...